Demographic Characteristics, Clinical Presentation And In-hospital Outcome Among Patients With Covid-19 In A Nigerian Tertiary Hospital

Author: Juliet I. Mmerem1,2*, Uche S. Unigwe1,3, Michael O. Iroezindu1 , Kyrian S. Chukwu1,3, Ifeyinwa. L. Ezenwosu4 , Geofrey O. Okorie1,5, Nneka M. Chika-Igwenyi1,3, Chidinma B. Nwatu1 , Obinna D. Onodugo1

Year: 2023

Category: Unpublished Journals

Abstract

The coronavirus disease 2019 (COVID-19) was discovered in Wuhan, Hubei province of China in December 2019 following a series of events heralded by a cluster of “mysterious” pneumonia cases1 . It was subsequently declared a pandemic by the World health organization (WHO) on 11th March, 20212 . As of 13th August 2021, a total of 205,338,159 confirmed cases and at least 4,333,094 confirmed deaths had been reported globally to the WHO3 . Several countries have already experienced multiple waves of the pandemic. In Nigeria, COVID-19 was first confirmed on 27th February 2020 following an imported case in an Italian businessman4 . This was relentlessly followed by widespread community transmission3 . As of 15th August 2021, Nigeria was experiencing a third wave of the outbreak with a total of 181,962 confirmed cases, including 2,219 deaths since the onset of the pandemic5,6. Several studies have been undertaken in various parts of the world to characterize COVID-197–11. So far, the literature from sub-Saharan Africa has been limited partly due to the impact of the pandemic on an already fragile healthcare system12,13. It is established that disease severity varies from asymptomatic to critical disease, which may require intensive care and may lead to mortality14–16. Older age and pre-existing co-morbidities such as chronic lung disease, hypertension, diabetes, and cardiovascular disease among others have been associated with more severe disease and increased mortality7,16,17. Healthcare worker exposure remains a source

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